CUNY 2010 will be held at the NYU Law School, which is located at 40 Washington Square South, the southwest corner of Washington Square Park, at the intersection of Washington Square South (aka West 4th St.) and MacDougal St. The spoken presentation sessions will be held in Tishman Hall. Poster sessions will be held in the Greenburg Lounge.
For information on restaurants, hotels, transportation, and parking, see NYU's Campus Information page.
For those short on copious amounts of disposable income, here are two recent articles from the NY Times about staying frugally in New York: